Basic Information

Symbol
hsa-mir-16-1
RNA class
miRNA miRNA hairpin
Alias
MIR16-1 MicroRNA 16-1 Hsa-MiR-16-1-3p Hsa-MiR-16-5p Hsa-Mir-16-1 MIRN16-1 Hsa-Mir-15-P2a_pre MIMAT0000069 MIMAT0004489 MiRNA16-1 MI0000070 Mir-16-1
Location (GRCh38)
19:51693254-51693339
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis Wound age identification
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-16-1
Sequence length
89 nt
GC content
0.4045

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-37.00 kcal/mol
Thermodynamic ensemble
Free energy: -37.76 kcal/mol
Frequency: 0.2922
Diversity: 5.27
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((..(((.((((((((((((.((((((((.(.(((..........))).).)))))))).)).)))))))))).)))..))))))
Thermodynamic Ensemble Prediction
((((((..(((.((((((((((((.((((((((.(.{{(..,.......))).).)))))))).)).)))))))))).)))..))))))
Forensic Context

A study in human trauma patients demonstrated that the mir-16-1 was significantly upregulated in circulating T cells during the injury stage compared to the recovery stage [Rau et al. DOI:10.2147/JIR.S375881]. In a separate forensic investigation on human postmortem brain tissue, the mir-16-1 was significantly upregulated in traumatic brain injury (TBI) cases versus controls, with its expression significantly higher in cases with short survival and in the critical–fatal TBI subgroup [Consalvo et al. DOI:10.3390/ijms25179539].