Basic Information

Symbol
hsa-mir-18b
RNA class
miRNA miRNA hairpin
Alias
MIR18B MicroRNA 18b Hsa-MiR-18b-5p Hsa-MiR-18b-3p Hsa-Mir-18b MIRN18B Hsa-Mir-17-P2c_pre MIMAT0001412 MIMAT0004751 MI0001518 Mir-18b hsa-mir-18-b
Location (GRCh38)
X:134170041-134170111
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-18b
Sequence length
71 nt
GC content
0.4648

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-18.90 kcal/mol
Thermodynamic ensemble
Free energy: -21.23 kcal/mol
Frequency: 0.0228
Diversity: 9.40
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((...((((.((((.(((.(((((.((................))))))).))).)))).))))...)))
Thermodynamic Ensemble Prediction
.{(,,,((((.((((.(((.(((((.{(,.,.....,,,.....}}))))).))).)))).))))..,))}
Forensic Context

A study in humans demonstrated that the mir-18b was upregulated 7.47-fold in denatured dermis compared to paired normal skin four days post-burn [Liang et al. DOI:10.1016/j.burns.2011.10.014], and a subsequent review confirmed its upregulation four days post-burn in deep partial thickness burn skin [Siu et al. DOI:10.1111/wrr.13100].