Forensic Context

A study in humans identified 66 differentially expressed miRNAs in denatured dermis from deep burn patients compared to paired normal skin, with the miR-18b-3p being upregulated 7.47-fold [Liang et al. DOI:10.1016/j.burns.2011.10.014]. A subsequent review confirmed the miR-18b-3p is upregulated in deep partial thickness burn skin four days post-injury, establishing its association with the burn wound healing process [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the miR-18b-3p was differentially expressed in blood samples from monozygotic twin pairs, with its expression shared across two pairs of twins, indicating its potential as a biomarker for distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].