Basic Information

Symbol
hsa-mir-184
RNA class
miRNA miRNA hairpin
Alias
MIR184 MicroRNA 184 Hsa-Mir-184 Hsa-MiR-184 MIRN184 Hsa-Mir-184_pre MIMAT0000454 MI0000481 MiR-184 EDICT
Location (GRCh38)
22:37847678-37847774
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis Mechanical injury analysis Wound age identification
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-184
Sequence length
84 nt
GC content
0.4881

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-37.70 kcal/mol
Thermodynamic ensemble
Free energy: -38.75 kcal/mol
Frequency: 0.2703
Diversity: 3.20
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(((((((.(.(((((((((.((((((.(.(((((((((......)))).))))).))))))).))))))))).).))))))).
Thermodynamic Ensemble Prediction
.(((((((.(.(((((((((.((((((.(.((((({((,......,})}.))))).))))))).))))))))).).))))))).
Forensic Context

A study in humans demonstrated that the mir-184 was differentially expressed, being downregulated in sepsis versus healthy controls and in septic shock versus healthy controls [Li et al. DOI:10.1038/s41598-025-89946-6]. In a separate study in Sprague-Dawley rats, the mir-184 was upregulated 10.50-fold in burn and 17.73-fold in hindlimb unloading, and was associated with decreased expression of its target genes *obp3* and *chad* [Song et al. DOI:10.1097/BCR.0000000000000444]. A study in rats demonstrated that the expression level of the mir-184 in serum significantly decreased following a burn injury, with lower levels correlating with greater burn severity and longer post-burn time, showing positive correlations with burn degree (r=0.901) and time after burn (r=0.732) [Xu et al. DOI:10.3892/etm.2019.7578].