Basic Information

Symbol
hsa-mir-185
RNA class
miRNA miRNA hairpin
Alias
MIR185 MicroRNA 185 Hsa-MiR-185-3p Hsa-MiR-185-5p Hsa-Mir-185 MIRN185 Hsa-Mir-185_pre MIMAT0000455 MIMAT0004611 MI0000482 MiR-185
Location (GRCh38)
Forensic tag(s)
Tissue/body fluid identification

Sequence & Structure

Transcript ID
hsa-mir-185
Sequence length
82 nt
GC content
0.6341

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-51.70 kcal/mol
Thermodynamic ensemble
Free energy: -52.20 kcal/mol
Frequency: 0.4478
Diversity: 5.50
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the mir-185 is a highly over-expressed miRNA marker for venous blood identification, confirmed by RT-PCR validation [Zubakov et al. DOI:10.1007/s00414-009-0402-3]. Subsequent genome-wide microarray screening also reported the mir-185 as exhibiting a good blood-specific expression pattern, supporting its utility as a stable marker for body fluid identification [Park et al. DOI:10.1002/elps.201400075].