Basic Information

Symbol
hsa-mir-187
RNA class
miRNA miRNA hairpin
Alias
MIR187 MicroRNA 187 Hsa-MiR-187-5p Hsa-MiR-187-3p Hsa-Mir-187 MIRN187 Hsa-Mir-187_pre MIMAT0000262 MIMAT0004561 MI0000274 MiRNA187 MiR-187
Location (GRCh38)
2:55988950-55989059
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-187
Sequence length
109 nt
GC content
0.6514

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-47.30 kcal/mol
Thermodynamic ensemble
Free energy: -49.72 kcal/mol
Frequency: 0.0198
Diversity: 22.93
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(.((((((.............((((...((((.((((.(((((((((((.((((.((......).).)).)).))))))))))).)))).))))..))))))))))).
Thermodynamic Ensemble Prediction
.,.{(({((({{,.{......,|||}}}.|(((.((((.(((((((((((.{(((.{{......).}})).}).))))))))))).)))).)))|{{|,,..)))),,.
Forensic Context

A study in Sprague-Dawley rats identified 68 differentially expressed miRNAs in the corpus cavernosum of obese rats with erectile dysfunction, where the mir-187 was downregulated 0.62-fold [Bai et al. DOI:10.1016/j.esxm.2017.06.006]. A review of human skin burns and wound healing reported that hsa-miR-187-3p was downregulated 0.62-fold in the corpus cavernosum of obese rats with erectile dysfunction and is also downregulated in hypertrophic scar tissue versus normal skin in humans [Siu et al. DOI:10.1111/wrr.13100]. A study in mice demonstrated that the mir-187 was significantly upregulated in the traumatized cortex following controlled cortical impact-induced traumatic brain injury, with an 8.82-fold increase observed during secondary contusion expansion [Meissner et al. DOI:10.1089/neu.2015.4077].