Basic Information

Symbol
hsa-mir-188
RNA class
miRNA miRNA hairpin
Alias
MIR188 MicroRNA 188 Hsa-MiR-188-3p Hsa-MiR-188-5p Hsa-Mir-188 MIRN188 Hsa-Mir-188-P1_pre MIMAT0000457 MIMAT0004613 MI0000484 MiR-188
Location (GRCh38)
6:45197674-45197770
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-188
Sequence length
86 nt
GC content
0.5814

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-38.60 kcal/mol
Thermodynamic ensemble
Free energy: -40.38 kcal/mol
Frequency: 0.0553
Diversity: 10.98
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((((((..(((..((..(((((((((..((((((....(.....).....))))))..)))))))))..))..))).)).)))).
Thermodynamic Ensemble Prediction
.((((((,.(((..((..(((((((((..(((((({...{.....}...,}))))))..)))))))))..))..))).)).)))).
Forensic Context

A study in humans demonstrated that mir-188, identified via miRNA sequencing as differentially expressed across five initial pairs of monozygotic twins, was validated by both qPCR and ddPCR as a candidate for distinguishing such individuals [Wang et al. DOI: 10.1016/j.fsigen.2025.103230]. A study in humans demonstrated that the mir-188 is an early biomarker for contrast-induced acute kidney injury [Shihana et al. DOI:10.1016/J.Toxlet.2020.09.003]. Another study in humans identified the mir-188 as a candidate for distinguishing monozygotic twins in peripheral blood, showing significant differential expression in all ten twin pairs tested via droplet digital PCR and exhibiting strong degradation resistance in bloodstains stored at room temperature for up to 180 days [Wang et al. DOI:10.1016/j.fsigen.2025.103230].