Basic Information

Symbol
hsa-mir-1908
RNA class
miRNA miRNA hairpin
Alias
MIR1908 MicroRNA 1908 Hsa-Mir-1908 Hsa-MiR-1908-5p MIRN1908 Hsa-Mir-1908_pre Hsa-MiR-1908-3p MIMAT0007881 MIMAT0026916 MI0008329 Mir-1908
Location (GRCh38)
11:61815161-61815240
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1908
Sequence length
80 nt
GC content
0.8000

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-46.20 kcal/mol
Thermodynamic ensemble
Free energy: -46.53 kcal/mol
Frequency: 0.5872
Diversity: 2.73
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((...((((.(((((((.(((((.(((((..((((.....)))).))))).))))).))))))).)))).))))....
Thermodynamic Ensemble Prediction
((((...((((.(((((((.(((((.(((((..((((.....)))).))))).))))).))))))).)))).))))....
Forensic Context

A study in human aortic endothelial cells demonstrated that the mir-1908 was repressed at 4 Gy-72h with multiple target mRNAs (e.g., VPS37D, GBP5) induced, identifying it as a mechanistic biomarker of radiation response [Chopra et al. DOI:10.1038/s41598-022-24051-6]. A study in rats demonstrated that the mir-1908 is upregulated in hypertrophic scars and targets Ski, suppressing its expression to enhance growth, collagen synthesis via increased TGF-β1, and pro-inflammatory markers (IL-1α, TNF-α), contributing to scar formation in burn models [Wang et al. DOI:10.1007/s00438-024-02183-w].