Basic Information

Symbol
hsa-miR-1908-3p
RNA class
miRNA mature miRNA
Alias
hsa-miR-1908 MIR1908 MicroRNA 1908
Location (GRCh38)
-
Forensic tag(s)
Cause of death analysis Wound age identification
External database

Sequence & Structure

Transcript ID
hsa-miR-1908-3p
Sequence length
21 nt
GC content
0.9524
Forensic Context

A study in human aortic endothelial cells demonstrated that the mir-1908 was repressed at 4 Gy-72h with multiple target mRNAs (e.g., VPS37D, GBP5) induced, identifying it as a mechanistic biomarker of radiation response [Chopra et al. DOI:10.1038/s41598-022-24051-6]. A study in rats demonstrated that the mir-1908 is upregulated in hypertrophic scars and targets Ski, suppressing its expression to enhance growth, collagen synthesis via increased TGF-β1, and pro-inflammatory markers (IL-1α, TNF-α), contributing to scar formation in burn models [Wang et al. DOI:10.1007/s00438-024-02183-w].