Basic Information

Symbol
hsa-mir-1915
RNA class
miRNA miRNA hairpin
Alias
MIR1915 MicroRNA 1915 Hsa-MiR-1915-3p Hsa-MiR-1915-5p Hsa-Mir-1915 MIRN1915 MIMAT0007891 MIMAT0007892 MI0008336
Location (GRCh38)
2:231892242-231892298
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1915
Sequence length
80 nt
GC content
0.7875

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-49.10 kcal/mol
Thermodynamic ensemble
Free energy: -50.10 kcal/mol
Frequency: 0.1980
Diversity: 4.94
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..((.((((((.(((((((.((.((((((((((..((....)).)))))..))))).)).))))))))))))))).....
Thermodynamic Ensemble Prediction
..((.((((((.(((((((.((.((((((((((.,((....)),)))))..))))).)).))))))))))))))).....
Forensic Context

A study in humans demonstrated that the mir-1915-3p was significantly downregulated in plasma-derived exosomes from male trauma patients compared to male operative controls, and it is known to drive hematopoietic stem/progenitor cells toward a megakaryocytic fate [Munley et al. DOI:10.1097/TA.0000000000004225]. Another human study investigating marathon-induced cardiac strain identified the mir-1915-3p as a diagnostic biomarker for myocardial infarction that is downregulated in MI, though it was only mentioned in the introduction and not experimentally studied in that specific exercise model [Shirvani Samani et al. DOI:10.3390/jcm11010005].