Basic Information

Symbol
hsa-mir-192
RNA class
miRNA miRNA hairpin
Alias
MIR192 MicroRNA 192 Hsa-MiR-192-5p Hsa-MiR-192-3p Hsa-Mir-192 MIRN192 Hsa-Mir-192-P2_pre MIMAT0000222 MIMAT0004543 MI0000234 MiRNA192 MiR-192
Location (GRCh38)
11:64891137-64891246
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis Wound age identification Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-192
Sequence length
110 nt
GC content
0.5727

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-39.00 kcal/mol
Thermodynamic ensemble
Free energy: -41.49 kcal/mol
Frequency: 0.0176
Diversity: 17.29
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.........(((.(((((.(.((.((((((((((((((.(((((((................))))))).))))).))))))))).)).).)))..))))).........
Thermodynamic Ensemble Prediction
,,.{,,...{{(,{,{{{.|.||,((((((((((((((.(((((((.,..............))))))).)))))},)))))))).}|,|.|}}..}}}})..,,},...
Forensic Context

A study in humans demonstrated that hsa-miR-192-5p was significantly upregulated in circulating T cells during the injury stage compared to the recovery stage in major trauma patients [Rau et al. DOI:10.2147/JIR.S375881]. In mice, serum mmu-miR-192-5p expression was significantly increased on day three only after lethal (10 Gy) total body irradiation, with its upregulation alleviated by amifostine pretreatment correlating with improved survival [Jia et al. DOI:10.1016/j.toxlet.2024.07.911]. A study in mice demonstrated that deep sequencing of thymus tissue following 4Gy whole-body ionizing radiation identified 112 differentially expressed miRNAs, including 45 known and 67 novel miRNAs, with 77 up-regulated and 35 down-regulated [Chen et al. DOI:10.1080/09553002.2016.1207821].