A study in humans demonstrated that hsa-miR-193a-5p was significantly upregulated in plasma from patients with acute spinal cord injury (SCI) at emergency room admission compared to healthy controls, as validated by droplet digital PCR [Hörauf et al. DOI:10.3390/ijms262210954]. In a separate human study, serum exosomal hsa-miR-193a-5p was identified as differentially expressed and was downregulated in patients with septic shock compared to those with sepsis [Li et al. DOI:10.1038/s41598-025-89946-6].