Basic Information

Symbol
hsa-mir-193b
RNA class
miRNA miRNA hairpin
Alias
MIR193B MicroRNA 193b Hsa-MiR-193b-3p Hsa-MiR-193b-5p Hsa-Mir-193b MIRN193B Hsa-Mir-193-P1a_pre MIMAT0002819 MIMAT0004767 MI0003137 Mir-193b
Location (GRCh38)
X:147272335-147272408
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Wound age identification Cause of death analysis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-193b
Sequence length
83 nt
GC content
0.4940

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-39.30 kcal/mol
Thermodynamic ensemble
Free energy: -40.92 kcal/mol
Frequency: 0.0723
Diversity: 6.57
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((((((((.(((((((((((((((.((.((.((.........)).)).)).))))))))))))))).))))))))))))
Thermodynamic Ensemble Prediction
((((((((((((.(((((((((((((((.((.((.(..........},,)).)).))))))))))))))).))))))))))))
Forensic Context

A study in humans demonstrated that the mir-193b was significantly increased in the plasma of myocardial infarction patients compared to healthy controls using next-generation sequencing, though RT-qPCR validation in an independent cohort showed no significant difference [Baulina et al. DOI:10.1016/j.yjmcc.2018.07.129]. In human skin wound healing, the mir-193b was downregulated 24 hours post-injury in skin wounds compared to unwounded skin, and it was also downregulated in hypertrophic scar tissue compared to normal tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that serum exosomal the mir-193b expression was significantly reduced in patients with sepsis and septic shock compared to healthy controls [Li et al. DOI:10.1038/s41598-025-89946-6].