A study in humans demonstrated that serum exosomal the miR-193b-5p is significantly reduced in patients with sepsis and septic shock compared to healthy controls, showing diagnostic potential with an AUC of 0.797 for sepsis and correlating inversely with inflammatory markers CRP, PCT, and IL-6 while positively correlating with lymphocyte count [Li et al. DOI:10.1038/s41598-025-89946-6].