Basic Information

Symbol
hsa-mir-103b-1
RNA class
miRNA miRNA hairpin
Alias
MIR103B1 MicroRNA 103b-1 Hsa-Mir-103-1-As Hsa-Mir-103b-1 MicroRNA 103-1-As MIRN103-1AS MIR103-1AS MIMAT0007402 Hsa-MiR-103b MIR103-1-AS MI0007261
Location (GRCh38)
5:168560904-168560965
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-103b-1
Sequence length
62 nt
GC content
0.4677

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-16.40 kcal/mol
Thermodynamic ensemble
Free energy: -17.32 kcal/mol
Frequency: 0.2260
Diversity: 4.76
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific dysregulation patterns observed in human skin tissue and cell lines post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in domestic swine demonstrated that the mir-103b was identified as a novel potential candidate primary microRNA (pri-miRNA) differentially regulated in heart tissue following induced myocardial infarction [Kaikkonen et al. DOI:10.1161/CIRCGENETICS.117.001702].