Basic Information

Symbol
hsa-mir-196b
RNA class
miRNA miRNA hairpin
Alias
MIR196B MicroRNA 196b Hsa-MiR-196b-3p Hsa-MiR-196b-5p Hsa-Mir-196b MIRN196B Hsa-Mir-196-P1_pre MIMAT0009201 MIMAT0001080 MiRNA196B MI0001150 MiR-196b
Location (GRCh38)
7:27169480-27169563
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis Mechanical injury analysis Wound age identification Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-196b
Sequence length
84 nt
GC content
0.4762

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-34.00 kcal/mol
Thermodynamic ensemble
Free energy: -34.60 kcal/mol
Frequency: 0.3782
Diversity: 2.03
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
(((((..((((((..(((((((.((.(((((((((((..........))))))))))).)).)))))))..)))))))))))..
Forensic Context

A study in humans demonstrated that the mir-196b was downregulated 4 days post-burn in deep partial thickness burn skin compared to normal skin [Siu et al. DOI:10.1111/wrr.13100] and was also downregulated 4 hours post-burn in heat-shocked fibroblasts versus a sham group [Siu et al. DOI:10.1111/wrr.13100]. In a separate investigation of human serum exosomes, the mir-196b was identified as differentially expressed and was downregulated in sepsis patients compared to healthy controls [Li et al. DOI:10.1038/s41598-025-89946-6]. A study in rhesus macaques (Macaca mulatta) demonstrated that the mir-196b was utilized as a feature in a Day 3 dose-prediction model and a Day 6 pleural effusion prediction model stratified by gender following whole thorax irradiation [May et al. DOI:10.1038/s41598-022-16316-x].