Basic Information

Symbol
hsa-mir-198
RNA class
miRNA miRNA hairpin
Alias
MIR198 MicroRNA 198 Hsa-Mir-198 Hsa-MiR-198 MIRN198 MIMAT0000228 MI0000240 MiR-198
Location (GRCh38)
3:120395668-120395729
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-198
Sequence length
62 nt
GC content
0.3871

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-13.80 kcal/mol
Thermodynamic ensemble
Free energy: -14.90 kcal/mol
Frequency: 0.5119
Diversity: 3.20
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
{((((..((...((((((((.(((..............)))))))))))...))...))))}
Forensic Context

A study in humans demonstrated that the mir-198 is upregulated four days post-burn in deep partial thickness burn skin compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. A study in mice demonstrated that elevated expression of the mir-198 in chronic wounds impairs keratinocyte migration and re-epithelialization [Badanina et al. DOI:10.3390/ijms262010060]. Research in human denatured dermis and heat-damaged fibroblasts further confirmed its dysregulation in thermal-induced skin injury, associating it with impaired wound healing processes [Wang & Zhou DOI:10.1007/s00438-024-02183-w].