Forensic Context

A study in humans demonstrated that the miR-200b-3p is downregulated in burn hypertrophic scar tissue compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the miR-200b-3p was a candidate marker for menstrual blood, showing high expression in several body fluids but with lesser discrimination ability, and it contributed to the successful differentiation of five forensically relevant body fluids using a set of 12 miRNAs [Altmeyer et al. DOI:10.1002/elps.202400089]. A study in mice identified the miR-200b-3p as an upregulated, apoptosis-related miRNA in myocardial tissue, where its expression showed a clear upward trend with increasing post-mortem interval, and a significant linear regression model was established for PMI estimation [Lee et al. DOI:10.1016/j.forsciint.2025.112473].