Basic Information

Symbol
hsa-mir-204
RNA class
miRNA miRNA hairpin
Alias
MIR204 MicroRNA 204 Hsa-MiR-204-5p Hsa-MiR-204-3p Hsa-Mir-204 MIRN204 Hsa-Mir-204-P2_pre MIMAT0022693 MIMAT0000265 MI0000284 MiRNA204 Mir-204 RDICC
Location (GRCh38)
10:17845107-17845193
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-204
Sequence length
110 nt
GC content
0.4818

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-42.00 kcal/mol
Thermodynamic ensemble
Free energy: -43.41 kcal/mol
Frequency: 0.1011
Diversity: 7.22
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.....((((..........(((((...(((((.((((((((((.(((((.((((...............))))))))).)))))))))).)))))...))))).))))..
Thermodynamic Ensemble Prediction
{{{....|}}......{,.(((((...(((((.((((((((((.(((((.((((...............))))))))).)))))))))).)))))...))))},}.)),.
Forensic Context

A study in mice demonstrated that the mir-204 showed a decreasing trend (5-fold) 5 to 10 days post-wounding, though this was not statistically significant when normalized to the stable reference gene RNU6B [Etich et al. DOI:10.1080/03008207.2016.1210606]. In a separate study in mice exposed to lethal total body irradiation, serum miR-204-5p was identified as an established oncogenic marker and was significantly downregulated (Log2(FC)=−5.24) in the early phase post-exposure [Chakraborty et al. DOI:10.1038/s41598-020-62255-w].