Forensic Context

A study in human tissues demonstrated that hsa-miR-208b-3p serves as a specific marker for heart muscle identification, showing distinctly higher expression in muscle versus non-muscle tissues and providing non-overlapping expression levels between heart and skeletal muscle [Sauer et al. DOI:10.1016/j.fsigen.2017.02.002]. A study in humans demonstrated that plasma extracellular vesicle miR-208b-3p is significantly upregulated in patients with acute coronary syndrome experiencing sudden cardiac death compared to healthy controls [Huang et al. DOI:10.1039/D2MO00257D].