Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns validated in human skin tissue and cell lines using qRT-PCR, microarrays, and next-generation sequencing [Siu et al. DOI:10.1111/wrr.13100]. A systematic review of the literature indicates that the mir-105 is inhibited by chronic morphine in the medial prefrontal cortex of rats, resulting in enhanced D1 receptor expression, and that its overexpression reduces morphine withdrawal conditioned place aversion [Occhipinti et al. DOI:10.3390/Ijms242317122].