Basic Information

Symbol
hsa-mir-212
RNA class
miRNA miRNA hairpin
Alias
MIR212 MicroRNA 212 Hsa-MiR-212-3p Hsa-MiR-212-5p Hsa-Mir-212 MIRN212 Hsa-Mir-132-P2_pre MIMAT0022695 MIMAT0000269 MI0000288 Mir-212
Location (GRCh38)
17:2050271-2050380
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis Wound age identification Forensic psychiatry evaluation Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-212
Sequence length
110 nt
GC content
0.7364

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-49.90 kcal/mol
Thermodynamic ensemble
Free energy: -50.58 kcal/mol
Frequency: 0.3331
Diversity: 5.33
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((...((....)).(((.(((.(((..((.(((((..((((((.((((((...(((...))).))))))))))))..))))).))...))).))))))))))))..
Thermodynamic Ensemble Prediction
((((((..,({....)).(((.(((.(((..((.(((((..((((((.((((((...(((...))).))))))))))))..))))).))...))).))))))))))))..
Forensic Context

A review of human studies identified the mir-212 as being upregulated six hours post-burn in heat-shocked skin epidermal stem cells compared to controls [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-212 is induced in the dorsal striatum of rats following chronic cocaine administration [Zhao et al. DOI:10.1007/s11411-016-9671-z], and a review of neurological diseases notes its role as a therapeutic target in schizophrenia, where it targets MMP-9, MeCP2, STAT4, and ZO-1, and is also induced in the dorsal striatum with cocaine exposure [Das et al. DOI:10.1080/21655979.2021.2003667].