Forensic Context

A study in humans analyzing 605 body fluid samples found that the miR-214-3p showed significant expression in menstrual blood, saliva, semen, and vaginal secretion [Liu et al. DOI:10.1093/bib/bbaa324]. A study in humans demonstrated that the miR-214-3p is a menstrual blood-specific marker, showing higher expression levels in menstrual blood and successfully contributing to the discrimination of five forensically relevant body fluids using a set of 12 miRNAs [Altmeyer et al. DOI:10.1002/elps.202400089]. A separate review noted that in mice, the miR-214-3p delivered via mesenchymal stem cell exosomes could inhibit the ATM/P53/P21 signaling pathway to mitigate ionizing radiation-induced lung injury [Jia & Wang DOI:10.3389/fcell.2022.861451].