Basic Information

Symbol
hsa-mir-217
RNA class
miRNA miRNA hairpin
Alias
MIR217 MicroRNA 217 Hsa-Mir-217 MiR-217 Hsa-MiR-217 MIRN217 Hsa-Mir-217-V1_pre Hsa-Mir-217-V2_pre Hsa-MiR-217-5p Hsa-MiR-217-3p MIMAT0037308 MIMAT0000274 MI0000293
Location (GRCh38)
2:55982967-55983076
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-217
Sequence length
110 nt
GC content
0.3636

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-31.60 kcal/mol
Thermodynamic ensemble
Free energy: -33.14 kcal/mol
Frequency: 0.0824
Diversity: 10.14
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(((.......)))...((((..(((((.(.((.((.(((((.((((((((((.((((........))).).)))))))))).))))).)).)).).))))).))))...
Thermodynamic Ensemble Prediction
.{{{.......}}}...((((..(((((.(.((.((.(((((.((((((((((.((((........))).).)))))))))).))))).)).)).).))))).))))...
Forensic Context

A study in mice identified 174 differentially expressed mature miRNAs in heart tissue exosomes following acute myocardial infarction, with in vitro validation showing that mimics of 19 selected miRNAs, including mmu-miR-30c-1-3p and mmu-miR-149-3p, significantly reduced hypoxic stress-induced cell death in primary cardiomyocytes [Jung et al. DOI:10.3390/biomedicines12020430].