Basic Information

Symbol
hsa-miR-218-2-3p
RNA class
miRNA mature miRNA
Alias
hsa-miR-218-2 MIR218-2 MicroRNA 218-2
Location (GRCh38)
-
Forensic tag(s)
Wound age identification
External database

Sequence & Structure

Transcript ID
hsa-miR-218-2-3p
Sequence length
22 nt
GC content
0.5909
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with the mir-218-2 being downregulated 4 days post-burn in deep partial thickness burn skin versus normal skin and downregulated 24 hours post-injury in skin wounds versus unwounded skin [Siu et al. DOI:10.1111/wrr.13100]. A study in rhesus macaques demonstrated that the mir-218-2 was utilized as a feature in a four-group survival prediction model at Day 3 and in a pleural effusion prediction model by gender at Day 21 following whole thorax irradiation [May et al. DOI:10.1038/s41598-022-16316-x].