A study in humans demonstrated that mir-23a-5p is differentially expressed in sepsis and septic shock, being downregulated in these patients compared to healthy controls [Li et al. DOI:10.1038/s41598-025-89946-6]. Another investigation in human peripheral blood found mir-23a-5p's expression to be correlated with age, though the direction of correlation was discordant between microarray and sequencing platforms [Meder et al. DOI:10.1373/clinchem.2014.224238].