Basic Information

Symbol
hsa-mir-24-1
RNA class
miRNA miRNA hairpin
Alias
MIR24-1 MicroRNA 24-1 Hsa-MiR-24-1-5p Hsa-MiR-24-3p Hsa-Mir-24-1 MIRN24-1 Hsa-Mir-24-P2_pre MIMAT0000079 MIMAT0000080 MicroRNA-24 MiRNA24-1 MI0000080 MiR-24-1 MIR189
Location (GRCh38)
9:95086021-95086088
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Forensic psychiatry evaluation Mechanical injury analysis Wound age identification
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-24-1
Sequence length
68 nt
GC content
0.5000

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-26.30 kcal/mol
Thermodynamic ensemble
Free energy: -26.86 kcal/mol
Frequency: 0.4040
Diversity: 1.66
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the mir-24-1 was significantly down-regulated in postmortem prefrontal cortex tissue from depressed suicide subjects compared to non-psychiatric controls [Smalheiser et al. DOI:10.1371/journal.pone.0033201]. In a separate review of human skin conditions, the mir-24-1 was also found to be downregulated in deep partial thickness burn skin four days post-injury compared to normal skin [Siu et al. DOI:10.1111/wrr.13100]. A study in rats demonstrated that the mir-24-1 was downregulated with a 1.71-fold change at 24 hours following oleic acid-induced acute lung injury [Lee et al. DOI:10.3892/Mmr.2014.2155].