Basic Information

Symbol
hsa-mir-27a
RNA class
miRNA miRNA hairpin
Alias
MIR27A MicroRNA 27a Hsa-MiR-27a-3p Hsa-MiR-27a-5p Hsa-Mir-27a MIRN27A Hsa-Mir-27-P3_pre MIMAT0004501 MIMAT0000084 MI0000085 Mir-27a MIR27
Location (GRCh38)
11:111512938-111513021
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis Wound age identification
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-27a
Sequence length
78 nt
GC content
0.6026

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-37.80 kcal/mol
Thermodynamic ensemble
Free energy: -38.85 kcal/mol
Frequency: 0.1813
Diversity: 4.51
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
(((.((.((.((((((((((((,,(((((((.((.{........})).)))))))))))))))))))).)).)).)))
Forensic Context

A study in human plasma demonstrated that hsa-miR-27a-3p was upregulated in patients with mild traumatic brain injury (TBI) compared to healthy controls [Qin et al. DOI:10.1371/journal.pone.0204051]. Conversely, a review of human skin tissue found hsa-miR-27a was downregulated in deep partial thickness burn skin four days post-burn and in skin wounds 24 hours post-injury [Siu et al. DOI:10.1111/wrr.13100].