Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with the miR-29b-1-5p being downregulated in differentiated myofibroblasts compared to untreated fibroblasts [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the miR-29b-1-5p was differentially expressed across three pairs of monozygotic twins, suggesting its potential role in distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003]. In a mouse model of methanol poisoning, the miR-29b-1-5p was upregulated in the liver tissue of female mice at 60 minutes and in the kidney tissue of female mice at all time points following an 8 g/kg dose [Gunay et al. DOI:10.1016/J.Fct.2023.113666].