Basic Information

Symbol
hsa-mir-29b-2
RNA class
miRNA miRNA hairpin
Alias
MIR29B2 MicroRNA 29b-2 Hsa-MiR-29b-2-5p Hsa-MiR-29b-3p Hsa-Mir-29b-2 MIRN29B2 Hsa-Mir-29-P1d-V1_pre Hsa-Mir-29-P1d-V2_pre MIMAT0000100 MIMAT0004515 Mir-29b-2 MI0000107 MiR-29b
Location (GRCh38)
1:207802443-207802523
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-29b-2
Sequence length
81 nt
GC content
0.3951

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-31.10 kcal/mol
Thermodynamic ensemble
Free energy: -32.81 kcal/mol
Frequency: 0.0619
Diversity: 4.93
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((((((((((((((((.((((((.((.((((..............)))))))))))).)))))))))).)))))))))
Thermodynamic Ensemble Prediction
(((((((({((((((((((.((((({,({{((((..............)))))))))))).)))))))))).}))))))))
Forensic Context

A study in human cardiac stromal cells from arrhythmogenic cardiomyopathy (ACM) patients demonstrated that the mir-29b-2 was significantly upregulated in ACM cells compared to healthy controls, with its target genes enriched in extracellular matrix organization pathways [Rainer et al. DOI:10.1186/s12864-018-4876-6]. In human skin, the mir-29b-2 was found to be downregulated in deep partial-thickness burn skin five days post-injury and in differentiated myofibroblasts, indicating its role in burn response and fibrotic scarring [Siu et al. DOI:10.1111/wrr.13100]. A study in rhesus macaques demonstrated that the mir-29b-2 was utilized as a feature in a Day 15 pleural effusion prediction model stratified by gender [May et al. DOI:10.1038/s41598-022-16316-x].