Basic Information

Symbol
hsa-mir-297
RNA class
miRNA miRNA hairpin
Alias
MIR297 MicroRNA 297 Hsa-Mir-297 Hsa-MiR-297 MIRN297 MIMAT0004450 MI0005775
Location (GRCh38)
2:175167633-175167709
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Postmortem interval inference Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-297
Sequence length
66 nt
GC content
0.2727

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-28.70 kcal/mol
Thermodynamic ensemble
Free energy: -29.94 kcal/mol
Frequency: 0.5204
Diversity: 4.13
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((.(((((((.((((((((((((((((((((....))))))))))))).))))))).)))))))))
Thermodynamic Ensemble Prediction
,(.(((((((.((((((((((((((((((((....)))))))))))))},)))))).)))))))),
Forensic Context

A study in rats demonstrated that the mir-297 was significantly upregulated in skeletal muscle at 24 hours postmortem with a fold change of 187.25, indicating its dysregulation during the early postmortem interval [Guardado-Estrada et al. DOI:10.7717/peerj.15409]. In a separate investigation in rats, the mir-297 was also found to be upregulated 1.57-fold in the corpus cavernosum of obese rats with erectile dysfunction, suggesting a potential role in this pathophysiological condition [Bai et al. DOI:10.1016/j.esxm.2017.06.006].