Basic Information
Symbol
hsa-miR-297
RNA class
miRNA
mature miRNA
Alias
hsa-miR-297
MIR297
MicroRNA 297
Location (GRCh38)
-
Forensic tag(s)
Postmortem interval inference
Other applications
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-28.70 kcal/mol
Thermodynamic ensemble
Free energy:
-29.94 kcal/mol
Frequency:
0.5204
Diversity:
4.13
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
,(.(((((((.((((((((((((((((((((....)))))))))))))},)))))).)))))))),
Forensic Context
A study in rats demonstrated that the miR-297 was significantly upregulated in skeletal muscle at 24 hours postmortem with a fold change of 187.25, indicating its dysregulation during the early postmortem interval [Guardado-Estrada et al. DOI:10.7717/peerj.15409]. In a separate investigation in rats, the miR-297 was also found to be upregulated 1.57-fold in the corpus cavernosum of obese rats with erectile dysfunction, suggesting a potential role in this pathophysiological condition [Bai et al. DOI:10.1016/j.esxm.2017.06.006].