Basic Information

Symbol
hsa-mir-299
RNA class
miRNA miRNA hairpin
Alias
MIR299 MicroRNA 299 Hsa-MiR-299-3p Hsa-MiR-299-5p Hsa-Mir-299 MIRN299 Hsa-Mir-154-P2-V1_pre Hsa-Mir-154-P2-V2_pre MIMAT0000687 MIMAT0002890 MI0000744 Mir-299
Location (GRCh38)
1:100281241-100281308
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-299
Sequence length
63 nt
GC content
0.3810

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-40.30 kcal/mol
Thermodynamic ensemble
Free energy: -40.79 kcal/mol
Frequency: 0.4524
Diversity: 1.03
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((.((((((((((((((((((((((.......)))))))))))))))))))))).)))))
Thermodynamic Ensemble Prediction
{((((.((((((((((((((((((((((.......)))))))))))))))))))))).))))}
Forensic Context

A study in humans demonstrated that the mir-299-5p is upregulated in burn hypertrophic scar tissue versus normal skin [Siu et al. DOI:10.1111/wrr.13100], and separate research on trauma patients found it downregulated in male plasma-derived exosomes compared to operative controls, where it is involved in hematopoiesis [Munley et al. DOI:10.1097/TA.0000000000004225]. A review of forensic miRNA biomarkers noted that the mir-299-5p has been identified as a plasma-specific marker and also as a placental-specific marker when up-regulated in maternal plasma [Silva et al. DOI:10.1016/J.Fsigen.2014.09.002].