Basic Information

Symbol
hsa-mir-1180
RNA class
miRNA miRNA hairpin
Alias
MIR1180 MicroRNA 1180 Hsa-Mir-1180 Hsa-MiR-1180-3p MIRN1180 Hsa-Mir-1180_pre Hsa-MiR-1180-5p MIMAT0005825 MIMAT0026735 MI0006273 Mir-1180
Location (GRCh38)
1:167998660-167998726
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1180
Sequence length
69 nt
GC content
0.6957

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-39.30 kcal/mol
Thermodynamic ensemble
Free energy: -40.19 kcal/mol
Frequency: 0.2358
Diversity: 4.77
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((((((((((.(((((((((((((..(....).))))))))))).)).))))))...))))))))
Thermodynamic Ensemble Prediction
((((((((((((((.(((((((((((({..(....),))))))))))).)).))))))...))))))))
Forensic Context

A study in humans demonstrated that plasma exosomal hsa-miR-1180-3p, identified as a high-abundance diagnostic biomarker, exhibited a downregulated expression pattern from healthy controls to coronary artery disease patients to acute myocardial infarction patients [Guo et al. DOI:10.21037/atm-20-2337]. A study in humans identified the mir-1180-3p as a high-abundance plasma exosomal microRNA with diagnostic potential for acute myocardial infarction, showing a downregulated expression pattern from healthy to coronary artery disease to AMI patient groups [Mei Guo et al. DOI:10.21037/atm-20-2337].