Forensic Context

A study in humans identified the miR-30a-5p as up-regulated in patients with ST-segment elevated myocardial infarction (STEMI) via small RNA sequencing [Tong et al. DOI:10.3390/ijms19051467]. A study in rats demonstrated that the miR-30a-5p was reported in literature to change after radiation but did not show changes in this model in blood between controls and irradiated rats at 2 weeks, with RT-qPCR results matching sequencing findings [Gao et al. DOI:10.1038/srep44132]. In human blood samples from monozygotic twins, the miR-30a-5p was identified as a differentially expressed microRNA shared across two pairs of twins, suggesting a role in distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].