Basic Information

Symbol
hsa-miR-30c-5p
RNA class
miRNA mature miRNA
Alias
hsa-miR-30c MIR30C MicroRNA 30c
Location (GRCh38)
-
Forensic tag(s)
Sudden cardiac death diagnosis Sudden death from CNS diseases
External database

Sequence & Structure

Transcript ID
hsa-miR-30c-5p
Sequence length
23 nt
GC content
0.4348
Forensic Context

A study in mice demonstrated that the miR-30c-5p is significantly downregulated during all stages of myocardial infarction and exerts anti-apoptotic effects in cardiomyocytes by directly targeting the pro-apoptotic genes Picalm and Skil [Kim et al. DOI:10.1038/s41598-018-33020-x]. In human patients with acute spinal cord injury, plasma levels of the miR-30c-5p were downregulated at emergency room admission and showed a divergent regulatory pattern compared to polytrauma patients without neurotrauma [Hörauf et al. DOI:10.3390/ijms262210954].