Forensic Context

A study in postmortem human myocardial infarction hearts demonstrated that the miR-30e-5p was significantly upregulated in both infarcted and non-infarcted regions compared to healthy controls, with its strongest increase observed in the non-infarcted myocardium [Wilmes et al. DOI:10.1016/J.Forsciint.2023.111892]. In a separate investigation of plasma from young human acute coronary syndrome patients, small RNA sequencing identified the miR-30e-5p as being upregulated in patients with ST-segment elevated myocardial infarction [Tong et al. DOI:10.3390/ijms19051467]. In a separate human study analyzing pericardial fluid from ST-segment elevation myocardial infarction patients, the miR-30e-5p was identified as one of several microRNAs augmented in this biofluid compared to controls [Silva et al. DOI:10.3390/ijms25158329].