Basic Information

Symbol
hsa-mir-31
RNA class
miRNA miRNA hairpin
Alias
MIR31 MicroRNA 31 Hsa-MiR-31-5p Hsa-MiR-31-3p Hsa-Mir-31 MIRN31 Hsa-Mir-31_pre MIMAT0000089 MIMAT0004504 MI0000089 MiR-31
Location (GRCh38)
9:21512115-21512185
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-31
Sequence length
71 nt
GC content
0.5070

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-36.80 kcal/mol
Thermodynamic ensemble
Free energy: -37.26 kcal/mol
Frequency: 0.4765
Diversity: 1.22
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A review of human studies found that the mir-31 is upregulated in hypertrophic scar tissue and its derived fibroblasts compared to normal skin and fibroblasts, and is also upregulated in skin wounds at 1 and 7 days post-injury [Siu et al. DOI:10.1111/wrr.13100]. In forensic wound identification, the mir-31 is involved in wound contraction and collagen deposition in mouse skin and has been confirmed as a novel biomarker for wound age estimation [Lei et al. DOI:10.1093/gpbjnl/qzag007].