Basic Information

Symbol
hsa-mir-3135a
RNA class
miRNA miRNA hairpin
Alias
MIR3135A MicroRNA 3135a Hsa-Mir-3135 MicroRNA 3135 MIR3135 Hsa-Mir-3135a Hsa-MiR-3135a MIMAT0015001 MI0014156
Location (GRCh38)
3:20137565-20137641
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Drug abuse diagnoses
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-3135a
Sequence length
77 nt
GC content
0.5584

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-32.80 kcal/mol
Thermodynamic ensemble
Free energy: -34.99 kcal/mol
Frequency: 0.7530
Diversity: 2.42
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((.((.(((((((..(((.(((((((((.((.......))))))))))).))).....)))))))))))))))
Thermodynamic Ensemble Prediction
{(((({{((.(((((((.,(((.(((((((((.((.......)}))))))))).))),....))))))))))))))}
Forensic Context

A study in humans identified the mir-3135a as a top upregulated circulating microRNA in patients with acute myocardial infarction compared to non-AMI controls, validated by qRT-PCR [Zhong et al. DOI:10.1002/jcla.23099]. In a separate human study, the mir-3135a was found to be upregulated in ethanol-exposed human embryonic stem cell-derived cortical interneurons, indicating its involvement in alcohol-induced transcriptomic changes [Lim et al. DOI:10.1038/s41398-021-01635-w].