Basic Information

Symbol
hsa-mir-3145
RNA class
miRNA miRNA hairpin
Alias
MIR3145 MicroRNA 3145 Hsa-MiR-3145-3p Hsa-Mir-3145 Hsa-Mir-3145_pre Hsa-MiR-3145-5p MIMAT0015016 MIMAT0019205 MI0014170 Mir-3145
Location (GRCh38)
Forensic tag(s)
Individual identification Drug abuse diagnoses

Sequence & Structure

Transcript ID
hsa-mir-3145
Sequence length
82 nt
GC content
0.3171

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-43.30 kcal/mol
Thermodynamic ensemble
Free energy: -43.87 kcal/mol
Frequency: 0.3951
Diversity: 1.62
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((((((((((.(((((((((((((((((((((.(.....).))))))...))))))))))))))).)))))))))))))
Thermodynamic Ensemble Prediction
{((((((((((((.(((((((((((((((((((((.(.....).))))))...))))))))))))))).))))))))))))}
Forensic Context

A study in humans demonstrated that recreational alcohol consumption significantly altered serum microRNA profiles, with the mir-3145-5p showing a 3.17-fold increase after exposure [Ten Berg et al. DOI:10.1080/1354750X.2018.1499128]. Separately, research in human monozygotic twins identified the mir-3145-5p as differentially expressed, being shared across two pairs of twins, indicating its potential role in distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].