Basic Information

Symbol
hsa-mir-3146
RNA class
miRNA miRNA hairpin
Alias
MIR3146 MicroRNA 3146 Hsa-Mir-3146 Hsa-Mir-3146_pre MIMAT0015018 Hsa-MiR-3146 MI0014172 Mir-3146
Location (GRCh38)
7:19705358-19705436
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-3146
Sequence length
79 nt
GC content
0.3797

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-46.60 kcal/mol
Thermodynamic ensemble
Free energy: -47.38 kcal/mol
Frequency: 0.2829
Diversity: 2.34
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the mir-3146 is a differentially expressed microRNA shared across three pairs of monozygotic twins, as identified through miRNA microarray analysis of blood samples and validated by qRT-PCR, indicating its potential role in distinguishing genetically identical individuals for forensic identification [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003]. In rhesus macaques, the mir-3146 was identified as a feature in a gender-specific model for predicting the future onset of pleural effusion following thoracic irradiation [May et al. DOI:10.1038/s41598-022-16316-x].