Basic Information
Symbol
hsa-miR-3146
RNA class
miRNA
mature miRNA
Alias
hsa-miR-3146
MIR3146
MicroRNA 3146
Location (GRCh38)
-
Forensic tag(s)
Individual identification
Other applications
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-46.60 kcal/mol
Thermodynamic ensemble
Free energy:
-47.38 kcal/mol
Frequency:
0.2829
Diversity:
2.34
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context
A study in humans demonstrated that the miR-3146 is a differentially expressed microRNA shared across three pairs of monozygotic twins, as identified through miRNA microarray analysis of blood samples and validated by qRT-PCR, indicating its potential role in distinguishing genetically identical individuals for forensic identification [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003]. In rhesus macaques, the miR-3146 was identified as a feature in a gender-specific model for predicting the future onset of pleural effusion following thoracic irradiation [May et al. DOI:10.1038/s41598-022-16316-x].