Forensic Context

A study in humans identified hsa-miR-3158-3p as a differentially expressed microRNA, with its expression downregulated in the peripheral whole blood of sepsis patients compared to healthy controls [Qin et al. DOI: 10.1097/JCMA.0000000000000209]. Another human study found the miR-3158-3p was upregulated in serum exosomes from both sepsis and septic shock patients relative to healthy controls and was identified as a critical miRNA within a differentially expressed miRNAs-mRNAs network [Li et al. DOI: 10.1038/s41598-025-89946-6].