A study in human umbilical vein endothelial cells (HUVECs) demonstrated that exosomal hsa-miR-1202 was significantly downregulated (fold change 10.23) in cells exposed to heat stroke temperature conditions (41°C) compared to normal controls, identifying it as a potential noninvasive biomarker for heat stroke [Chen et al. DOI:10.12659/MSM.909983]. In a separate investigation, the mir-1202 was mentioned as being downregulated in the prefrontal cortex of individuals with major depressive disorder and as regulating GRM4, based on prior literature discussed in the introduction [Lopez et al. DOI:10.1038/ncomms15497].