Basic Information

Symbol
hsa-mir-3185
RNA class
miRNA miRNA hairpin
Alias
MIR3185 MicroRNA 3185 Hsa-Mir-3185 MIMAT0015065 Hsa-MiR-3185 MI0014227
Location (GRCh38)
4:5923275-5923328
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-3185
Sequence length
68 nt
GC content
0.6324

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-39.80 kcal/mol
Thermodynamic ensemble
Free energy: -40.30 kcal/mol
Frequency: 0.7347
Diversity: 3.23
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in human cardiac tissue demonstrated that the mir-3185 is significantly upregulated in cases of mechanical asphyxia compared to deaths from craniocerebral injury, hemorrhagic shock, sudden cardiac death, and poisoning, with its expression showing no correlation with postmortem interval, age, or temperature [Han et al. DOI:10.1016/j.forsciint.2020.110293]. A review notes the mir-3185 is part of a molecular prediction model for determining mechanical asphyxia death in human myocardium [Li et al. DOI:10.1093/fsr/owad003].