Basic Information

Symbol
hsa-mir-3186
RNA class
miRNA miRNA hairpin
Alias
MIR3186 MicroRNA 3186 Hsa-Mir-3186 Hsa-MiR-3186-5p Hsa-MiR-3186-3p MIMAT0015067 MIMAT0015068 MI0014229 Mir-3186
Location (GRCh38)
17:81451104-81451188
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-3186
Sequence length
85 nt
GC content
0.5647

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-44.90 kcal/mol
Thermodynamic ensemble
Free energy: -45.72 kcal/mol
Frequency: 0.2628
Diversity: 3.04
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
(((((..((((((((.((.(((((.(((.((((((((.{({...}}}..)))))))).))).))))).))))))))))..)))))
Forensic Context

A study in humans demonstrated that plasma exosomal hsa-miR-3186-5p, a low-abundance miRNA, was uniquely elevated in acute myocardial infarction (AMI) patients compared to healthy and coronary artery disease (CAD) groups, where it could not be detected, and was part of an 18-miRNA panel with a diagnostic AUC of 0.87 for AMI [Guo et al. DOI:10.21037/atm-20-2337].