Basic Information

Symbol
hsa-mir-3189
RNA class
miRNA miRNA hairpin
Alias
MIR3189 MicroRNA 3189 Hsa-Mir-3189 Hsa-MiR-3189-5p Hsa-MiR-3189-3p MIMAT0019217 MIMAT0015071 MI0014233 Mir-3189
Location (GRCh38)
15:49169070-49169153
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-3189
Sequence length
73 nt
GC content
0.6027

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-36.50 kcal/mol
Thermodynamic ensemble
Free energy: -37.50 kcal/mol
Frequency: 0.1960
Diversity: 5.25
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
((.((.(((((((((((.{.((((.((((((((...)))))....)))..))))}.))))))))))).)).))
Forensic Context

A study in humans with coronary artery disease identified the mir-3189-3p as a biomarker for recurrent myocardial infarction risk, where it was downregulated in whole blood of patients with recurrent MI compared to those without, remaining significant after false-discovery rate correction (FDR <0.1) in the replication cohort, though it was not significantly different in plasma samples [Onuoha et al. DOI:10.1111/cts.13307].