Basic Information
Symbol
hsa-miR-3197
RNA class
miRNA
mature miRNA
Alias
hsa-miR-3197
MIR3197
MicroRNA 3197
Location (GRCh38)
-
Forensic tag(s)
Tissue/body fluid identification
Other applications
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-38.90 kcal/mol
Thermodynamic ensemble
Free energy:
-40.30 kcal/mol
Frequency:
0.2706
Diversity:
4.02
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
(((((((((({{((..((.((((.((((.((..{......,..)).)))).)))).))..)))))))))))))
Forensic Context
A study in humans identified the miR-3197 as a novel semen-specific miRNA marker for forensic body fluid identification, demonstrating high overexpression in semen and high sensitivity and specificity with an AUC of approximately 0.97 in validation [Park et al. DOI:10.1002/elps.201400075]. Separately, research in human cells showed the miR-3197 is upregulated in a dose-dependent manner at 4 and 24 hours post-ionizing radiation exposure in human lymphoblastoid AHH-1 cells and in human peripheral blood lymphocytes irradiated ex vivo, identifying it as a radiation exposure biomarker [Song et al. DOI:10.3390/life10120361].