Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs like hsa-miR-21 and hsa-miR-31 upregulated in hypertrophic scar tissue and shown to promote keratinocyte proliferation and migration [Siu et al. DOI:10.1111/wrr.13100]. A study in mice demonstrated that the miR-329-3p is up-regulated in plasma after low dose radiation (10 mGy or 100 mGy) [Jia et al. DOI:10.3389/fcell.2022.861451], while in rats subjected to transient ischaemic attack, plasma exosomal rno-miR-329-3p was down-regulated following 10 minutes of cerebral ischaemia [Li et al. DOI:10.3389/fnagi.2018.00024].