Basic Information

Symbol
hsa-mir-33a
RNA class
miRNA miRNA hairpin
Alias
MIR33A MicroRNA 33a Hsa-MiR-33a-3p Hsa-MiR-33a-5p Hsa-Mir-33a Hsa-Mir-33 MicroRNA 33 MIRN33A MIRN33 Hsa-Mir-33-P3_pre MIMAT0000091 MIMAT0004506 MI0000091 MiRNA33A Mir-33a MiR-33 MIR33
Location (GRCh38)
1:156420341-156420429
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-33a
Sequence length
69 nt
GC content
0.4783

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-36.40 kcal/mol
Thermodynamic ensemble
Free energy: -36.86 kcal/mol
Frequency: 0.4757
Diversity: 1.82
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((((((((((.(..((((((((((....(((...)))))))))))))..).))))))))))))))
Thermodynamic Ensemble Prediction
((((((((((((((.(..((((((((((....(((...)))))))))))))..).))))))))))))))
Forensic Context

A study in non-human primates (Macaca mulatta) demonstrated that plasma levels of the mir-33a-3p at or below the median abundance at day 6 post whole-thorax lung irradiation were associated with significantly reduced survival and 100% mortality before 175 days [Rogers et al. DOI:10.1667/RADE-20-00031.1]. A study in mice demonstrated that methamphetamine-induced locomotor sensitization involves significant downregulation of the mir-33a-3p in the nucleus accumbens, alongside dysregulation of miRNA biogenesis factors Ago2 and Dicerl [Liu et al. DOI:10.1111/Adb.12616].